Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fgf signaling regulates development and transdifferentiation of hair cells and supporting cells in the basilar papilla.

Hearing research - 1 Jul 2012

Jacques Bonnie E, Dabdoub Alain, Kelley Matthew W

Abstract excerpt

The avian basilar papilla (BP) is a likely homolog of the auditory sensory epithelium of the mammalian cochlea, the organ of Corti. During mammalian development Fibroblast growth factor receptor-3 (Fgfr3) is known to regulate the differentiation of auditory mechanosensory hair cells (HCs) and supporting cells (SCs), both of which are required for sound detection. Fgfr3 is expressed in developing progenitor cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Transdifferentiation
Share to Fibroblast Growth Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hair Cells, Auditory

Share to Organ Culture Techniques

Share to Organ of Corti

Share to Pyrroles

Share to Receptors, Fibroblast Growth Factor

Share to SOXB1 Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 22575790
DOI: 10.1016/j.heares.2012.04.018
PMCID: PMC3412397

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fgf signaling regulates development and transdifferentiation of hair cells and supporting cells in the basilar papilla.PMID 22575790Read ↗

FGFR1 is required for the development of the auditory sensory epithelium.Semantic proximity Read ↗

FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis.Semantic proximity Read ↗

MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear.Semantic proximity Read ↗

Development and Regeneration of the Inner EarSemantic proximity Read ↗

Differential requirements for FGF3, FGF8 and FGF10 during inner ear development.Semantic proximity Read ↗

Single-Cell Transcriptomic Profiling of the Zebrafish Inner Ear Reveals Molecularly Distinct Hair Cell and Supporting Cell SubtypesSemantic proximity Read ↗

Insulin-Like Growth Factor Signaling Regulates the Timing of Sensory Cell Differentiation in the Mouse CochleaSemantic proximity Read ↗

Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3.Semantic proximity Read ↗

Inner ear supporting cells: rethinking the silent majority.Semantic proximity Read ↗

Conserved role of Sonic Hedgehog in tonotopic organization of the avian basilar papilla and mammalian cochlea.Semantic proximity Read ↗

Characterization of supporting cell phenotype in the avian inner ear: implications for sensory regeneration.Semantic proximity Read ↗

Forced activation of Wnt signaling alters morphogenesis and sensory organ identity in the chicken inner ear.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.