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Article

Implication of NOTCH1 gene in susceptibility to anxiety and depression among sexual abuse victims.

Translational psychiatry - 13 Dec 2016

Steine I M, Zayats T, Stansberg C, Pallesen S, Mrdalj J, Håvik B, Soulé J, Haavik J, Milde A M, Skrede S, Murison R, Krystal J, Grønli J

Abstract excerpt

Sexual abuse contributes to the development of multiple forms of psychopathology, including anxiety and depression, but the extent to which genetics contributes to these disorders among sexual abuse victims remains unclear. In this translational study, we first examined gene expression in the brains of rodents exposed to different early-life conditions (long, brief or no maternal separation). Hypothesizing that...

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Source

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Identifiers

PMID: 27959334
DOI: 10.1038/tp.2016.248
PMCID: PMC5290341

Genes

NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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