Article
Colonial history and contemporary transmission shape the genetic diversity of hepatitis C virus genotype 2 in Amsterdam.
Journal of virology - 1 Jul 2012
Markov Peter V, van de Laar Thijs J, Thomas Xiomara V, Aronson Sem J, Weegink Christine J, van den Berk Guido E, Prins Maria, Pybus Oliver G, Schinkel Janke
Abstract excerpt
Evolutionary analysis of hepatitis C virus (HCV) genome sequences has provided insights into the epidemic history and transmission of this widespread human pathogen. Here we report an exceptionally diverse set of 178 HCV genotype 2 (HCV-2) isolates from 189 patients in Amsterdam, comprising 8 distinct HCV subtypes and 10 previously not recognized, unclassified lineages. By combining study subjects' demographic...
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