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Phylogenetic analysis reveals three distinct epidemiological profiles in Dutch and Flemish blood donors with hepatitis B virus infection.

Virology - 1 Feb 2018

van de Laar Thijs J, Van Gaever Véronique A, Swieten Peter van, Muylaert An, Compernolle Veerle, Zaaijer Hans L

Abstract excerpt

During 2006-2016, hepatitis B virus (HBV) was detected in nearly 400 blood donors in the Netherlands and Flanders. Donor demographics and self-reported risk factors as disclosed during the donor exit interview were compared to HBV phylogenies of donor and reference sequences. First-time donors with chronic HBV-infection were often immigrants (67%) infected with genetically highly diverse strains of genotypes A...

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PMID: 29324289
DOI: 10.1016/j.virol.2017.12.011

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