Article
Next-Generation Sequencing Reveals Continued Circulation of Rare HIV-1 Subtypes in the Democratic Republic of the Congo and Refines the Estimate of the Emergence Dates of Three Subtypes.
Viruses - 21 Feb 2026
Anderson Mark, Orf Gregory S, Holzmayer Vera, Olivo Ana, Harris Barbara J, Berg Michael G, Yu Guixia, Achari Asmeeta, Federman Scot, Chiu Charles Y, James Linda, Mampunza Samuel, Cloherty Gavin A, Rodgers Mary A
Abstract excerpt
HIV-1 diversified for decades within the Democratic Republic of the Congo (DRC) before spreading globally in the early 1980s. Thus, the DRC is home to some of the most ancestral and diverse HIV-1 strains. Recent serosurveys conducted from 2017 to 2019 in Kinshasa, DRC, indicated high prevalence of HIV-1, yet sequence data is lacking from this period. Given the history of circulating rare HIV-1 subtypes in the...
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