Article
Next-Generation Sequencing Reveals Frequent Opportunities for Exposure to Hepatitis C Virus in Ghana.
PloS one - 1 Jan 2015
Forbi Joseph C, Layden Jennifer E, Phillips Richard O, Mora Nallely, Xia Guo-Liang, Campo David S, Purdy Michael A, Dimitrova Zoya E, Owusu Dorcas O, Punkova Lili T, Skums Pavel, Owusu-Ofori Shirley, Sarfo Fred Stephen, Vaughan Gilberto, Roh Hajung, Opare-Sem Ohene K, Cooper Richard S, Khudyakov Yury E
Abstract excerpt
Globally, hepatitis C Virus (HCV) infection is responsible for a large proportion of persons with liver disease, including cancer. The infection is highly prevalent in sub-Saharan Africa. West Africa was identified as a geographic origin of two HCV genotypes. However, little is known about the genetic composition of HCV populations in many countries of the region. Using conventional and next-generation sequencing...
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