Article
IPGWAS: an integrated pipeline for rational quality control and association analysis of genome-wide genetic studies.
Biochemical and biophysical research communications - 8 Jun 2012
Fan Yan-Hui, Song You-Qiang
Abstract excerpt
Large numbers of samples and marker loci were tested for association in genome-wide association studies (GWAS). Hence, quality control (QC) by removing individuals or markers with low genotyping quality is of utmost importance to minimize potential false positive associations. IPGWAS was developed to facilitate the identification of the rational thresholds in QC of GWAS datasets, association analysis, Manhattan...
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