Article

Pre- and post-genotype filtration protocol to improve the variant imputation metrics with further quality control

2023-01-19

Abstract excerpt

<title>Abstract</title> <p>The search for loci linked to diseases or drug targets is being studied by genotyping variants. Missing variants can be imputed, but the standard filtration methods applied during quality control(QC) reduced their number for downstream analyses.There is no standard protocol to retain the maximum of variants with reliable quality. To counteract this loss, we first limited the stringency...

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Literature Corpus work: b6837d42-8a26-5835-8d3e-d64cd7097c96
DOI: 10.21203/rs.3.pex-2088/v1

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