Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Residue Ile89 in human plasma membrane monoamine transporter influences its organic cation transport activity and sensitivity to inhibition by dilazep.

Biochemical pharmacology - 1 Aug 2012

Ho Horace T B, Xia Li, Wang Joanne

Abstract excerpt

Plasma membrane monoamine transporter (PMAT) is a polyspecific organic cation transporter belonging to the equilibrative nucleoside transporter (ENT) family. Despite its distinct substrate specificity from the classic nucleoside transporters ENT1 and 2, PMAT appears to share similar protein archi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cell Line
Share to Cell Membrane

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ion Transport

Share to Isoleucine

Share to Membrane Transport Proteins

Share to Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 22562044
DOI: 10.1016/j.bcp.2012.04.018
PMCID: PMC3372611

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22562044-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Residue Ile89 in human plasma membrane monoamine transporter influences its organic cation transport activity and sensitivity to inhibition by dilazep.PMID 22562044Read ↗

Mutation of Trp29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity.Semantic proximity Read ↗

The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoformsSemantic proximity Read ↗

Glutamate 346 of human Na+-H+ exchanger NHE1 is crucial for modulating both the affinity for Na+ and the interaction with amiloride derivatives.Semantic proximity Read ↗

Investigation of the functional roles of the MELAL and GQXXRXG motifs of the human noradrenaline transporter using cysteine mutants.Semantic proximity Read ↗

Thr136Ile polymorphism of human vesicular monoamine transporter-1 (SLC18A1 gene) influences its transport activity in vitro.Semantic proximity Read ↗

Cysteine residues in the transmembrane (TM) 9 to TM11 region of the human equilibrative nucleoside transporter subtype 1 play an important role in inhibitor binding and translocation function.Semantic proximity Read ↗

Genetic variants in multidrug and toxic compound extrusion-1, hMATE1, alter transport function.Semantic proximity Read ↗

Residues 334 and 338 in transmembrane segment 8 of human equilibrative nucleoside transporter 1 are important determinants of inhibitor sensitivity, protein folding, and catalytic turnover.Semantic proximity Read ↗

Importance of His192 in the human thyroid hormone transporter MCT8 for substrate recognition.Semantic proximity Read ↗

The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29.Semantic proximity Read ↗

Mutation of the aromatic amino acid interacting with adenine moiety of ATP to a polar residue alters the properties of multidrug resistance protein 1.Semantic proximity Read ↗

Equilibrative nucleoside transporters-A review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.