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Article

Phosphorylation of Rab11-FIP2 regulates polarity in MDCK cells.

Molecular biology of the cell - 1 Jun 2012

Lapierre Lynne A, Avant Kenya M, Caldwell Cathy M, Oztan Asli, Apodaca Gerard, Knowles Byron C, Roland Joseph T, Ducharme Nicole A, Goldenring James R

Abstract excerpt

The Rab11 effector Rab11-family interacting protein 2 (Rab11-FIP2) regulates transcytosis through its interactions with Rab11a and myosin Vb. Previous studies implicated Rab11-FIP2 in the establishment of polarity in Madin-Darby canine kidney (MDCK) cells through phosphorylation of Ser-227 by MAR...

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Source

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Identifiers

PMID: 22553350
DOI: 10.1091/mbc.E11-08-0681
PMCID: PMC3374749

Genes

MARK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22553350-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Phosphorylation of Rab11-FIP2 regulates polarity in MDCK cells.PMID 22553350Read ↗

MARK2/EMK1/Par-1Balpha phosphorylation of Rab11-family interacting protein 2 is necessary for the timely establishment of polarity in Madin-Darby canine kidney cells.Semantic proximity Read ↗

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Rab11-FIP2 functions in transferrin recycling and associates with endosomal membranes via its COOH-terminal domain.Semantic proximity Read ↗

IRSp53 shapes the plasma membrane and controls polarized transport at the nascent lumen during epithelial morphogenesisSemantic proximity Read ↗

AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells.Semantic proximity Read ↗

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Myosin-1c regulates the dynamic stability of E-cadherin-based cell-cell contacts in polarized Madin-Darby canine kidney cells.Semantic proximity Read ↗

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