Article
Neutralization resistance of virological synapse-mediated HIV-1 Infection is regulated by the gp41 cytoplasmic tail.
Journal of virology - 1 Jul 2012
Durham Natasha D, Yewdall Alice W, Chen Ping, Lee Rebecca, Zony Chati, Robinson James E, Chen Benjamin K
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) infection can spread efficiently from infected to uninfected T cells through adhesive contacts called virological synapses (VSs). In this process, cell-surface envelope glycoprotein (Env) initiates adhesion and viral transfer into an uninfected recipient cell. Previous studies have found some HIV-1-neutralizing patient sera to be less effective at blocking VS-mediated...
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