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Article

A study of prostaglandin pathway genes and interactions with current nonsteroidal anti-inflammatory drug use in colorectal adenoma.

Cancer prevention research (Philadelphia, Pa.) - 1 Jun 2012

Edwards Todd L, Shrubsole Martha J, Cai Qiuyin, Li Guoliang, Dai Qi, Rex Douglas K, Ulbright Thomas M, Fu Zhenming, Murff Harvey J, Smalley Walter, Ness Reid, Zheng Wei

Abstract excerpt

Colorectal cancer (CRC) is the second leading cause of cancer-related death and usually arises from colorectal polyps. Screening and removal of polyps reduce mortality from CRC. Colorectal polyps are known to aggregate in families; however the genetic determinants for risk of polyps are unknown. In addition, it has been shown that nonsteroidal anti-inflammatory drug (NSAID) use decreases the risk of CRC and the...

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Share to Adenoma
Share to Anti-Inflammatory Agents, Non-Steroidal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22551900
DOI: 10.1158/1940-6207.CAPR-11-0459
PMCID: PMC3789595

Genes

HPGD
PTGER2
PTGER3
PTGER4
PTGS2

Provenance

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