Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Jun 2012

Anbalagan Selvakumar, Pires Isabel M, Blick Christopher, Hill Mark A, Ferguson David J P, Chan Denise A, Hammond Ester M

Abstract excerpt

BACKGROUND AND PURPOSE: For patients diagnosed with advanced renal cell carcinoma (RCC), there are few therapeutic options. Radiation therapy is predominantly used to treat metastasis and has not proven effective in the adjuvant setting for renal cancer. Furthermore, RCC is resistant to standard...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Renal Cell
Share to Cell Hypoxia
Share to Radiation Dosage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Radiation Tolerance

Share to Sirolimus

Share to Thiazoles

Share to Tumor Stem Cell Assay

Share to Von Hippel-Lindau Tumor Suppressor Protein

Source

Identifiers

PMID: 22551566
DOI: 10.1016/j.radonc.2012.04.001

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22551566-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy.PMID 22551566Read ↗

A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces AutophagySemantic proximity Read ↗

Atractylenolide I inhibits angiogenesis and reverses sunitinib resistance in clear cell renal cell carcinoma through ATP6V0D2-mediated autophagic degradation of EPAS1/HIF2αSemantic proximity Read ↗

Inhibiting autophagy: a novel approach for the treatment of renal cell carcinoma.Semantic proximity Read ↗

Inhibition of STAT1 sensitizes renal cell carcinoma cells to radiotherapy and chemotherapySemantic proximity Read ↗

A HIF-Regulated VHL-PTP1B-Src Signaling Axis Identifies a Therapeutic Target in Renal Cell CarcinomaSemantic proximity Read ↗

Repression of the autophagic response sensitises lung cancer cells to radiation and chemotherapySemantic proximity Read ↗

Effect of radiation and ibuprofen on normoxic renal carcinoma cells overexpressing hypoxia-inducible factors by loss of von Hippel-Lindau tumor suppressor gene function.Semantic proximity Read ↗

2'-hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma.Semantic proximity Read ↗

Inhibition of the DNA-Dependent Protein Kinase Catalytic Subunit Radiosensitizes Malignant Glioma Cells by Inducing AutophagySemantic proximity Read ↗

The Radiosensitizing Effect of AZD0530 in Glioblastoma and Glioblastoma Stem-Like CellsSemantic proximity Read ↗

Mitochondrial Dysfunctions Regulated Radioresistance through Mitochondria-to-Nucleus Retrograde Signaling Pathway of NF-κB/PI3K/AKT2/mTORSemantic proximity Read ↗

Targeting Epidermal Growth Factor Receptor–Associated Signaling Pathways in Non–Small Cell Lung Cancer Cells: Implication in Radiation ResponseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.