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Article

Common patterns and disease-related signatures in tuberculosis and sarcoidosis

30 Apr 2012

Abstract excerpt

In light of the marked global health impact of tuberculosis (TB), strong focus has been on identifying biosignatures. Gene expression profiles in blood cells identified so far are indicative of a persistent activation of the immune system and chronic inflammatory pathology in active TB. Definition of a biosignature with unique specificity for TB demands that identified profiles can differentiate diseases with...

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PMID: 22547807
DOI: 10.1073/pnas.1121072109

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