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Article

Systematic analysis of metallo-β-lactamases using an automated database.

Antimicrobial agents and chemotherapy - 1 Jul 2012

Widmann Michael, Pleiss Jürgen, Oelschlaeger Peter

Abstract excerpt

Metallo-β-lactamases (MBLs) are enzymes that hydrolyze β-lactam antibiotics, resulting in bacterial resistance to these drugs. These proteins have caused concerns due to their facile transference, broad substrate spectra, and the absence of clinically useful inhibitors. To facilitate the classification, nomenclature, and analysis of MBLs, an automated database system was developed, the Metallo-β-Lactamase...

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PMID: 22547615
DOI: 10.1128/AAC.00255-12
PMCID: PMC3393435

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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