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Article

Genetic characterization of gliomas arising in patients with multiple sclerosis.

Journal of neuro-oncology - 1 Sept 2012

Khalil Adam, Serracino Hilary, Damek Denise M, Ney Douglas, Lillehei Kevin O, Kleinschmidt-DeMasters B K

Abstract excerpt

The co-occurrence of gliomas and multiple sclerosis (MS) in the same patient is uncommon, but a well-reported phenomenon. Most have been high grade astrocytic tumors that developed after the diagnosis of MS, leading authors to postulate that chronic gliosis in demyelinative plaques might be the underlying substrate for secondary induction of a glial neoplasm. Until recently, however, genetic tools have not been...

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Source

Identifiers

PMID: 22547311
DOI: 10.1007/s11060-012-0888-2

Genes

IDH1
EGFR
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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