Article
Gliosarcomas with the BRAF V600E mutation: a report of two cases and review of the literature.
Journal of clinical pathology - 1 Dec 2017
Wang Leiming, Sun Jian, Li Zhuo, Chen Li, Fu Yongjuan, Zhao Lihong, Liu Li, Wei Yukui, Teng Lianghong, Lu Dehong
Abstract excerpt
Gliosarcoma, which is regarded as a variant of glioblastoma, is a rare malignant neoplasm of the central nervous system. Both its sarcomatous component and glial component are reported to share significant clinical and genetic similarities. However, gliosarcomas are considered to be characterised by a lack of the BRAF V600E mutation. Here, we report two cases of gliosarcoma harbouring the BRAF V600E mutation, of...
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