Article
Pregnancy and the methyltransferase genotype independently influence the arsenic methylation phenotype.
Pharmacogenetics and genomics - 1 Jul 2012
Gardner Renee M, Engström Karin, Bottai Matteo, Hoque Waheedul A M, Raqib Rubhana, Broberg Karin, Vahter Marie
Abstract excerpt
OBJECTIVES: The methyltransferase genotype and pregnancy both influence the arsenic metabolism phenotype, but it is unknown whether these factors interact, explaining the drastic changes in the efficiency of arsenic metabolism observed among pregnant women. The aim of this study was to evaluate the relative contribution of the methyltransferase genotype and pregnancy to the arsenic metabolism phenotype. METHODS:...
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