Article
PTHrP and breast cancer: more than hypercalcemia and bone metastases.
Breast cancer research : BCR - 25 Apr 2012
Boras-Granic Kata, Wysolmerski John J
Abstract excerpt
Parathyroid hormone-related protein (PTHrP) causes hypercalcemia in cancer patients. PTHrP is required for normal breast development and has been shown to promote bone metastases from breast cancers. However, whether the protein also contributes to the formation of primary tumors has been unclear. Two recent papers suggest it may. First, a report in Nature Genetics identified the PTHrP locus as a new breast...
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