Article
The putative Walker A and Walker B motifs of Rrp2 are required for the growth of Borrelia burgdorferi.
Molecular microbiology - 1 Jan 2017
Ouyang Zhiming, Zhou Jianli
Abstract excerpt
Rrp2 encodes a putative bacterial enhancer binding protein (bEBP) in Borrelia burgdorferi. Point mutation (G239C) of Rrp2 abolishes the transcriptional activation of σ54 -dependent rpoS. In contrast to canonical bEBPs that are dispensable for bacterial growth, Rrp2 is essential for borrelial growth in BSK medium. It has been believed that Rrp2's ATPase activity is not required for cell growth, but experimental...
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