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Article

Understanding and tuning the catalytic bias of hydrogenase.

Journal of the American Chemical Society - 23 May 2012

Abou Hamdan Abbas, Dementin Sébastien, Liebgott Pierre-Pol, Gutierrez-Sanz Oscar, Richaud Pierre, De Lacey Antonio L, Rousset Marc, Bertrand Patrick, Cournac Laurent, Léger Christophe

Abstract excerpt

When enzymes are optimized for biotechnological purposes, the goal often is to increase stability or catalytic efficiency. However, many enzymes reversibly convert their substrate and product, and if one is interested in catalysis in only one direction, it may be necessary to prevent the reverse...

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Identifiers

PMID: 22540997
DOI: 10.1021/ja301802r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22540997-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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