Candidate gene study of genetic thrombophilic polymorphisms in pre-eclampsia and recurrent pregnancy loss in Sinhalese women.

doi:10.1111/j.1447-0756.2012.01846.x

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Article

Candidate gene study of genetic thrombophilic polymorphisms in pre-eclampsia and recurrent pregnancy loss in Sinhalese women.

The journal of obstetrics and gynaecology research - 1 Sept 2012

Dissanayake Vajira H W, Sirisena Nirmala D, Weerasekera Lakshini Y, Gammulla Chumithri G, Seneviratne Harshalal R, Jayasekara Rohan W

Abstract excerpt

AIM: Genetic thrombophilias are known to contribute to adverse pregnancy outcomes. Studies in Western populations show that 5, 10-methylenetetrahydrofolate reductase (MTHFR) 677C>T and Factor V (F5) 1691G>A (Leiden) polymorphisms are commonly associated with pre-eclampsia and recurrent spontaneous pregnancy loss. The objective of this study was to investigate the association of MTHFR 677C>T (rs1801133); 1298A>C...

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PMID: 22540831
DOI: 10.1111/j.1447-0756.2012.01846.x

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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