Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MTHFR 1298A>C Substitution is a Strong Candidate for Analysis in Recurrent Pregnancy Loss: Evidence from 14,289 Subjects.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Apr 2022

Mehta Poonam, Vishvkarma Rahul, Singh Kiran, Rajender Singh

Abstract excerpt

We undertook meta-analyses on MTHFR 1298A>C substitution for critically evaluating its association with recurrent pregnancy loss (RPL). MTHFR genotype data for 5888 cases and 8401 controls from 39 studies were pooled to perform this meta-analyses. Genotype data were screened, scrutinized, pooled, analysed and subjected to sensitivity analysis to carefully evaluate the association between MTHFR 1298A>C and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Habitual
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Single Nucleotide

Share to Pregnancy

Source

Identifiers

PMID: 33742421
DOI: 10.1007/s43032-021-00530-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MTHFR 1298A>C Substitution is a Strong Candidate for Analysis in Recurrent Pregnancy Loss: Evidence from 14,289 Subjects.PMID 33742421Read ↗

Association between maternal, fetal and paternal MTHFR gene C677T and A1298C polymorphisms and risk of recurrent pregnancy loss: a comprehensive evaluation.Semantic proximity Read ↗

Variants c.677 C>T, c.1298 A>C in MTHFR, and c.66 A>G in MTRR Affect the Occurrence of Recurrent Pregnancy Loss in Chinese Women.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms and recurrent pregnancy loss in China: a systematic review and meta-analysis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene A1298C polymorphism and susceptibility to recurrent pregnancy loss: a meta-analysis.Semantic proximity Read ↗

Thrombophilic gene polymorphisms and recurrent pregnancy loss: a systematic review and meta-analysis.Semantic proximity Read ↗

MTHFR C677T polymorphism and recurrent early pregnancy loss risk in north Indian population.Semantic proximity Read ↗

Association of maternal and fetal MTHFR A1298C polymorphism with the risk of pregnancy loss: a study of an Indian population and a meta-analysis.Semantic proximity Read ↗

The association between methionine synthase reductase c.66A>G variant and the risk of recurrent pregnancy loss: A systematic review and meta-analysis.Semantic proximity Read ↗

Association study between methylenetetrahydrofolate reductase polymorphisms and unexplained recurrent pregnancy loss: a meta-analysis.Semantic proximity Read ↗

A meta-analysis for association of eNOS VNTR 4b/a, - 786 T > C and + 894G > T polymorphisms with risk of recurrent pregnancy loss.Semantic proximity Read ↗

Role of miRNA polymorphism in recurrent pregnancy loss: a systematic review and meta-analysis.Semantic proximity Read ↗

Association between FVL G1691A, FII G20210A, and MTHFR C677T and A1298C polymorphisms and Turkish women with recurrent pregnancy loss.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.