Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New ZNF644 mutations identified in patients with high myopia.

Molecular vision - 1 Jan 2014

Xiang Xinying, Wang Tianyun, Tong Ping, Li Yunping, Guo Hui, Wan Anran, Xia Lu, Liu Yanling, Li Ying, Tian Qi, Shen Lu, Cai Xinzhang, Tian Lei, Jin Xuemin, Xia Kun, Hu Zhengmao

Abstract excerpt

PURPOSE: Myopia, or near-sightedness, is one of the most common human visual impairments worldwide, and high myopia is one of the leading causes of blindness. In this study, we investigated the mutation spectrum of ZNF644, a causative gene for autosomal dominant high myopia, in a high-myopia cohort from a Chinese population. METHODS: DNA was isolated with the standard proteinase K digestion and phenol-chloroform...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to DNA Mutational Analysis

Share to Myopia

Share to Refractive Errors

Share to Transcription Factors

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 24991186
PMCID: PMC4077594

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New ZNF644 mutations identified in patients with high myopia.PMID 24991186Read ↗

Exome sequencing identifies ZNF644 mutations in high myopia.Semantic proximity Read ↗

Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility.Semantic proximity Read ↗

Mutational investigation of 17 causative genes in a cohort of 113 families with nonsyndromic early-onset high myopia in northwestern China.Semantic proximity Read ↗

Detection of mutations in LRPAP1, CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2 in 298 families with early-onset high myopia by exome sequencing.Semantic proximity Read ↗

Mutational screening of AGRN, SLC39A5, SCO2, P4HA2, BSG, ZNF644, and CPSF1 in a Chinese cohort of 103 patients with nonsyndromic high myopia.Semantic proximity Read ↗

Screening of genes interacting with high myopia and neuropsychiatric disorders.Semantic proximity Read ↗

Variants in HNRNPH1 are associated with high myopia in humans and ocular coloboma in zebrafish.Semantic proximity Read ↗

Mutation screening of 17 candidate genes in a cohort of 67 probands with early-onset high myopia.Semantic proximity Read ↗

Association of ZNF644, GRM6, and CTNND2 genes with high myopia in the Han Chinese population: Jiangsu Eye Study.Semantic proximity Read ↗

[Association of ZNF644, GRM6 and CTNND2 genes polymorphisms with high myopia].Semantic proximity Read ↗

Identification of seven novel ZNF469 mutations in keratoconus patients in a Han Chinese population.Semantic proximity Read ↗

A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.