Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A β-Lactamase based reporter system for ESX dependent protein translocation in mycobacteria.

PloS one - 1 Jan 2012

Rosenberger Tobias, Brülle Juliane K, Sander Peter

Abstract excerpt

Protein secretion is essential for all bacteria in order to interact with their environment. Mycobacterium tuberculosis depends on protein secretion to subvert host immune response mechanisms. Both the general secretion system (Sec) and the twin-arginine translocation system (Tat) are functional in mycobacteria. Furthermore, a novel type of protein translocation system named ESX has been identified. In the genome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ampicillin
Share to beta-Lactamases
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Order

Share to Genes, Reporter

Share to Mycobacterium

Share to Protein Transport

Share to Recombinant Fusion Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 22530024
DOI: 10.1371/journal.pone.0035453
PMCID: PMC3329429

Genes

CFP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A β-Lactamase based reporter system for ESX dependent protein translocation in mycobacteria.PMID 22530024Read ↗

ESX/Type VII Secretion Systems—An Important Way Out for Mycobacterial ProteinsSemantic proximity Read ↗

ESX secretion system: The gatekeepers of mycobacterial survivability and pathogenesisSemantic proximity Read ↗

Polarly localized EccE <sub>1</sub> is required for ESX-1 function and stabilization of ESX-1 membrane proteins in <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

Polarly Localized EccE1 Is Required for ESX-1 Function and Stabilization of ESX-1 Membrane Proteins in Mycobacterium tuberculosis.Semantic proximity Read ↗

The regulatory functions of ESX-1 substrates, EspE and EspF, are separable from secretionSemantic proximity Read ↗

Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulatorSemantic proximity Read ↗

WhiB6 is required for the secretion-dependent regulation of ESX-1 substrates in pathogenic mycobacteriaSemantic proximity Read ↗

EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 SystemSemantic proximity Read ↗

The twin-arginine translocation pathway of Mycobacterium smegmatis is functional and required for the export of mycobacterial beta-lactamases.Semantic proximity Read ↗

The plasmid-mediated evolution of the mycobacterial ESX (Type VII) secretion systemsSemantic proximity Read ↗

Master control of protein secretion by <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

PPE and PE_PGRS proteins of <i>Mycobacterium marinum</i> are transported via the type VII secretion system ESX‐5Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.