Article
Cardiac myosin binding protein C and MAP-kinase activating death domain-containing gene polymorphisms and diastolic heart failure.
PloS one - 1 Jan 2012
Wu Cho-Kai, Huang Yin-Tsen, Lee Jen-Kuang, Chiang Liang-Ting, Chiang Fu-Tien, Huang Shu-Wei, Lin Jiunn-Lee, Tseng Chuen-Den, Chen Yau-Hung, Tsai Chia-Ti
Abstract excerpt
OBJECTIVE: Myosin binding protein C (MYBPC3) plays a role in ventricular relaxation. The aim of the study was to investigate the association between cardiac myosin binding protein C (MYBPC3) gene polymorphisms and diastolic heart failure (DHF) in a human case-control study. METHODS: A total of 352 participants of 1752 consecutive patients from the National Taiwan University Hospital and its affiliated hospital...
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