Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adverse events in families with hypertrophic or dilated cardiomyopathy and mutations in the MYBPC3 gene.

BMC medical genetics - 28 Oct 2008

Ehlermann Philipp, Weichenhan Dieter, Zehelein Jörg, Steen Henning, Pribe Regina, Zeller Raphael, Lehrke Stephanie, Zugck Christian, Ivandic Boris T, Katus Hugo A

Abstract excerpt

BACKGROUND: Mutations in MYBPC3 encoding myosin binding protein C belong to the most frequent causes of hypertrophic cardiomyopathy (HCM) and may also lead to dilated cardiomyopathy (DCM). MYBPC3 mutations initially were considered to cause a benign form of HCM. The aim of this study was to examine the clinical outcome of patients and their relatives with 18 different MYBPC3 mutations. METHODS: 87 patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiomyopathy, Hypertrophic, Familial

Share to Carrier Proteins

Share to Echocardiography

Share to Magnetic Resonance Imaging

Share to Pedigree

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 18957093
DOI: 10.1186/1471-2350-9-95
PMCID: PMC2584029

Genes

MYBPC3
MYH7
TNNI3
TNNT2
TPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adverse events in families with hypertrophic or dilated cardiomyopathy and mutations in the MYBPC3 gene.PMID 18957093Read ↗

Spectrum of MYBPC3 Gene Mutations in Patients with Hypertrophic Cardiomyopathy, Reporting Two Novel Mutations from North-West of Iran.Semantic proximity Read ↗

Spectrum of clinical phenotypes and gene variants in cardiac myosin-binding protein C mutation carriers with hypertrophic cardiomyopathy.Semantic proximity Read ↗

A founder MYBPC3 mutation results in HCM with a high risk of sudden death after the fourth decade of life.Semantic proximity Read ↗

Clinical Characteristics and Long-Term Outcome of Hypertrophic Cardiomyopathy in Individuals With a MYBPC3 (Myosin-Binding Protein C) Founder Mutation.Semantic proximity Read ↗

Autosomal recessive transmission of MYBPC3 mutation results in malignant phenotype of hypertrophic cardiomyopathy.Semantic proximity Read ↗

Cardiac Myosin Binding Protein-C Mutations in Families With Hypertrophic CardiomyopathySemantic proximity Read ↗

An Update on MYBPC3 Gene Mutation in Hypertrophic Cardiomyopathy.Semantic proximity Read ↗

Insights into genotype-phenotype correlation in hypertrophic cardiomyopathy. Findings from 18 Spanish families with a single mutation in MYBPC3.Semantic proximity Read ↗

Clinical Features and Prognostic Implications of Familial Hypertrophic Cardiomyopathy Related to the Cardiac Myosin-Binding Protein C GeneSemantic proximity Read ↗

Clinical Outcome of Hypertrophic Cardiomyopathy in Probands with the Founder Variant c.913_914del in MYBPC3: A Slovenian Cohort Study.Semantic proximity Read ↗

Two novel mutations of the MYBPC3 gene identified in Chinese families with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Hypertrophic cardiomyopathy due to truncating variants in myosin binding protein C: a Spanish cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.