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Article

Association of 25 bp deletion in MYBPC3 gene with left ventricle dysfunction in coronary artery disease patients.

PloS one - 1 Jan 2011

Srivastava Anshika, Garg Naveen, Mittal Tulika, Khanna Roopali, Gupta Shipra, Seth Prahlad Kishore, Mittal Balraj

Abstract excerpt

RATIONALE: Mutations in MYBPC3 encoding cardiac myosin binding protein C are common genetic cause of hereditary cardiac myopathies. An intronic 25-bp deletion in MYBPC3 at 3' region is associated with dilated (DCM) and hypertrophic (HCM) cardiomyopathies in Southeast Asia. However, the frequency of MYBPC3 25 bp deletion and associated clinical presentation has not been established in an unrelated cohort of left...

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Source

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Identifiers

PMID: 21915287
DOI: 10.1371/journal.pone.0024123
PMCID: PMC3168477

Genes

MYBPC3
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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