Association of p53 codon 248 (exon7) with urinary bladder cancer risk in the North Indian population.

doi:10.5582/bst.2011.v5.5.205

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Article

Association of p53 codon 248 (exon7) with urinary bladder cancer risk in the North Indian population.

Bioscience trends - 1 Jan 2011

Jaiswal Praveen K, Goel Apul, Mittal Rama D

Abstract excerpt

p53 is the most frequently mutated gene in all forms of human cancer. It responds to diverse stresses including UVR-induced DNA damage and regulates many downstream genes to initiate cell-cycle arrest, DNA repair or apoptosis. p53 gene variants at codon 11, Pro47Ser and codon 248 (exon 7) were evaluated for bladder cancer (BC) risk in North Indians. In the present study, the above encoding regions in p53 genes...

Topics

Codon
Exons
Female
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Haplotypes
Humans
Immunotherapy
India
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mycobacterium bovis

Neoplasm Grading

Neoplasm Staging

Polymorphism, Single Nucleotide

Risk Factors

Smoking

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PMID: 22101376
DOI: 10.5582/bst.2011.v5.5.205

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