Article
A case-control nutrigenomic study on the synergistic activity of folate and vitamin B12 in cervical cancer progression.
Nutrition and cancer - 1 Jan 2012
Ragasudha Preethi N, Thulaseedharan Jissa V, Wesley Ramani, Jayaprakash P G, Lalitha Prema, Pillai M Radhakrishna
Abstract excerpt
The present study was designed to identify the role of folate, B12, homocysteine, and polymorphisms of methylene tetrahydrofolatereductase (MTHFR) gene in cervical carcinogenesis among 322 women from Kerala, South India. Serum folate, vitamin B12 (chemiluminescence assay), and homocysteine (EIA) along with genetic polymorphisms of MTHFR gene (polymerase chain reaction/restriction fragment length polymorphism)...
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