Article
The effects of polymorphisms in methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), and methionine synthase reductase (MTRR) on the risk of cervical intraepithelial neoplasia and cervical cancer in Korean women.
Cancer causes & control : CCC - 1 Jan 2010
Tong Seo-Yun, Lee Jong-Min, Song Eun-Seop, Lee Kwang-Beom, Kim Mi-Kyung, Yun Young Mi, Lee Jae-Kwan, Son Sung-Kyong, Lee Jung-Pil, Kim Jae-Hoon, Hur Soo-Young, Kwon Yong-Il
Abstract excerpt
The purpose of the study was to investigate the association between cervical cancer risk and single-nucleotide polymorphisms (SNPs) in three one-carbon metabolism genes, methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), and methionine synthase reductase (MTRR) in Korean women. Twelve SNPs were identified in MTHFR, MTR, and MTRR in the 927 case-control samples, which included 165 cervical...
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