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Article

FcγRIIb and BAFF differentially regulate peritoneal B1 cell survival.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2012

Amezcua Vesely María C, Schwartz Marc, Bermejo Daniela A, Montes Carolina L, Cautivo Kelly M, Kalergis Alexis M, Rawlings David J, Acosta-Rodríguez Eva V, Gruppi Adriana

Abstract excerpt

B1 cells produce most natural Abs in unimmunized mice and play a key role in the response to thymus-independent Ags and microbial infection. Enlargement of B1 cell number in mice is often associated with autoimmunity. However, the factors that control peripheral B1 cell survival remain poorly characterized. Mice lacking the inhibitory receptor FcγRIIb exhibit a massive expansion in peritoneal B1 cells,...

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Identifiers

PMID: 22516957
DOI: 10.4049/jimmunol.1102070
PMCID: PMC3361506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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