Article
Investigation of selected cytokine genes suggests that IL2RA and the TNF/LTA locus are risk factors for severe alopecia areata.
The British journal of dermatology - 1 Dec 2012
Redler S, Albert F, Brockschmidt F F, Herold C, Hanneken S, Eigelshoven S, Giehl K A, Kruse R, Lutz G, Wolff H, Blaumeiser B, Böhm M, Becker T, Nöthen M M, Betz R C
Abstract excerpt
BACKGROUND: Alopecia areata (AA) is the second most common cause of hair loss in humans, and has a genetically complex inheritance. The hypothesis that AA is autoimmune in nature is supported by previous studies. These report an association with specific HLA alleles, as well as genetic variants of other genes implicated in autoimmunity, such as various cytokine genes. However, these cannot yet be considered...
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