Article
BRAF, KIT, and NRAS Mutations of Acral Melanoma in White Patients.
American journal of clinical pathology - 15 Apr 2020
Dika Emi, Veronesi Giulia, Altimari Annalisa, Riefolo Mattia, Ravaioli Giulia Maria, Piraccini Bianca Maria, Lambertini Martina, Campione Elena, Gruppioni Elisa, Fiorentino Michelangelo, Melotti Barbara, Ferracin Manuela, Patrizi Annalisa
Abstract excerpt
OBJECTIVES: Malignant acral melanoma (AM) is relatively infrequent in white patients. Molecular investigations have returned variable results regarding the mutational pattern. We sought to describe the mutation profile and clinicopathologic features of AM. METHODS: We investigated BRAF, KIT, and NRAS mutational status in a series of 31 AM samples from white patients. RESULTS: Nodular melanoma was the most common...
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