Article
KIT amplification and gene mutations in acral/mucosal melanoma in Korea.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jun 2011
Yun Jina, Lee Jeeyun, Jang Jiryeon, Lee Eui Jin, Jang Kee Taek, Kim Jung Han, Kim Kyoung-Mee
Abstract excerpt
Mucosal and acral melanomas have demonstrated different genetic alterations and biological behavior compared with more common cutaneous melanomas. It was recently reported that gain-of-function KIT mutations and/or copy number increases are more common in mucosal and acral melanomas. Thus, we studied the frequency and pattern of KIT aberrations in mucosal and acral melanomas in Korea. We analyzed 97 patients who...
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