Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of a Novel Androgen Receptor Target Gene, the Cyclin B1 Gene, through Androgen-Dependent E2F Family Member Switching

17 Apr 2012

Abstract excerpt

The malignant transformation of human prostatic epithelium is associated with the loss of androgen receptor (AR) in the surrounding stroma. However, the function and mechanisms of AR signaling in prostate cancer (PCa) stroma remain elusive. Here we report, by using proteomics pathway array analysis (PPAA), that androgen and its receptor inhibit the proliferation of prostate stromal cells through transcriptional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cancer-related Molecular Pathways
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22508987
DOI: 10.1128/mcb.06663-11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of a Novel Androgen Receptor Target Gene, the Cyclin B1 Gene, through Androgen-Dependent E2F Family Member SwitchingPMID 22508987Read ↗

Cyclin D1 Is a Selective Modifier of Androgen-dependent Signaling and Androgen Receptor FunctionSemantic proximity Read ↗

Transcription Factors in Prostate Cancer: Insights for Disease Development and Diagnostic and Therapeutic ApproachesSemantic proximity Read ↗

Genome-wide crosstalk between steroid receptors in breast and prostate cancersSemantic proximity Read ↗

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancerSemantic proximity Read ↗

Androgen-regulated transcription of <i>ESRP2</i> drives alternative splicing patterns in prostate cancerSemantic proximity Read ↗

Differential impact of RB status on E2F1 reprogramming in human cancerSemantic proximity Read ↗

Key Genes And Pathways Controlled By E2F1 In Human Castration-Resistant Prostate Cancer CellsSemantic proximity Read ↗

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate CancerSemantic proximity Read ↗

Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner.Semantic proximity Read ↗

Estrogen receptor β exerts tumor suppressive effects in prostate cancer through repression of androgen receptor activitySemantic proximity Read ↗

ACTR/AIB1/SRC-3 and androgen receptor control prostate cancer cell proliferation and tumor growth through direct control of cell cycle genesSemantic proximity Read ↗

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.