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Article

Cyclin D1 Is a Selective Modifier of Androgen-dependent Signaling and Androgen Receptor Function

7 Jan 2011

Abstract excerpt

D-type cyclins regulate cellular outcomes in part through cyclin-dependent, kinase-independent mechanisms that modify transcription factor action, and recent in vivo studies showed that cyclin D1 associates with a large number of transcriptional regulators in cells of the retina and breast. Given the frequency of cyclin D1 alterations in cancer, it is imperative to delineate the molecular mechanisms by which...

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PMID: 21212260
DOI: 10.1074/jbc.m110.170720

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