Article
RNA-Seq analysis of frontal cortex and cerebellum from 5XFAD mice at early stage of disease pathology.
Journal of Alzheimer's disease : JAD - 1 Jan 2012
Kim Kyung Hwa, Moon Minho, Yu Saet-Byeol, Mook-Jung Inhee, Kim Jong-Il
Abstract excerpt
The pathogenesis of Alzheimer's disease (AD), especially the early events of AD pathology, remains unknown because of the complexity of AD and limitation of analysis methods. Transcriptome analysis has provided comprehensive insights to investigate the complex cellular activity in brain, but the transcriptome profiles from AD patients with microarray have generated discordant results. Here, for the first time, we...
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