Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood.

PLoS biology - 1 Jan 2012

Schaedel Oren N, Gerisch Birgit, Antebi Adam, Sternberg Paul W

Abstract excerpt

Many animals can choose between different developmental fates to maximize fitness. Despite the complexity of environmental cues and life history, different developmental fates are executed in a robust fashion. The nematode Caenorhabditis elegans serves as a powerful model to examine this phenomenon because it can adopt one of two developmental fates (adulthood or diapause) depending on environmental conditions....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans Proteins
Share to Cytochrome P-450 Enzyme System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Feedback, Physiological

Share to Hormones

Share to Life Cycle Stages

Share to Pheromones

Share to Reproduction

Source

Open in PubMed Open full text

Identifiers

PMID: 22505848
DOI: 10.1371/journal.pbio.1001306
PMCID: PMC3323525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hormonal signal amplification mediates environmental conditions during development and controls an irreversible commitment to adulthood.PMID 22505848Read ↗

A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans.Semantic proximity Read ↗

A conserved endocrine mechanism controls the formation of dauer and infective larvae in nematodes.Semantic proximity Read ↗

Dauer.Semantic proximity Read ↗

Integration of carbohydrate metabolism and redox state controls dauer larva formation in Caenorhabditis elegans.Semantic proximity Read ↗

daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans.Semantic proximity Read ↗

A histone H4 lysine 20 methyltransferase couples environmental cues to sensory neuron control of developmental plasticity.Semantic proximity Read ↗

A Natural Mutational Event Uncovers a Life History Trade-Off via Hormonal Pleiotropy.Semantic proximity Read ↗

daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans.Semantic proximity Read ↗

Both entry to and exit from diapause arrest in Caenorhabditis elegans are regulated by a steroid hormone pathway.Semantic proximity Read ↗

No Significant Increase in the Δ4- and Δ7-Dafachronic Acid Concentration in the Long-Lived glp-1 Mutant, nor in the Mutants Defective in Dauer Formation.Semantic proximity Read ↗

A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span.Semantic proximity Read ↗

Steroid hormone pathways coordinate developmental diapause and olfactory remodeling in Pristionchus pacificus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.