Article
Replication of associations between cytokine and cytokine receptor single nucleotide polymorphisms and measles-specific adaptive immunophenotypic extremes.
Human immunology - 1 Jun 2012
White Sarah J, Haralambieva Iana H, Ovsyannikova Inna G, Vierkant Robert A, O'Byrne Megan M, Poland Gregory A
Abstract excerpt
Our objective was to replicate previously reported associations between cytokine and cytokine receptor SNPs and humoral and CMI (cell-mediated immune) responses to measles vaccine. All subjects (n=758) received two doses of MMR (measles/mumps/rubella) vaccine. From these subjects, candidate cytokine and cytokine receptor SNPs were genotyped and analyzed in 29-30 subjects falling into one of four "extreme" humoral...
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