Article
Genetic polymorphisms associated with rubella virus-specific cellular immunity following MMR vaccination.
Human genetics - 1 Nov 2014
Kennedy Richard B, Ovsyannikova Inna G, Haralambieva Iana H, Lambert Nathaniel D, Pankratz V Shane, Poland Gregory A
Abstract excerpt
Rubella virus causes a relatively benign disease in most cases, although infection during pregnancy can result in serious birth defects. An effective vaccine has been available since the early 1970s and outbreaks typically do not occur among highly vaccinated (≥2 doses) populations. Nevertheless, considerable inter-individual variation in immune response to rubella immunization does exist, with single-dose...
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