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Article

Polymorphic variation in glutathione-S-transferase genes and risk of chronic myeloid leukaemia in the Kashmiri population.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Bhat Gulzar, Bhat Ashaqullah, Wani Aadil, Sadiq Nida, Jeelani Samoon, Kaur Rajinder, Masood Akbar, Ganai Bashir

Abstract excerpt

Cancer is a complex disease and the genetic susceptibility to it could be an outcome of the inherited difference in the capacity of xenobiotic metabolizing enzymes. Glutathione-S-transferases (GSTs) are phase II metabolizing enzymes whose various genotypes have been associated with increased risk of different types of cancer. Null mutations caused by the deletion of the entire gene result in the absence of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Source

Identifiers

PMID: 22502716
DOI: 10.7314/apjcp.2012.13.1.069

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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