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Article

optiCall: a robust genotype-calling algorithm for rare, low-frequency and common variants.

Bioinformatics (Oxford, England) - 15 Jun 2012

Shah T S, Liu J Z, Floyd J A B, Morris J A, Wirth N, Barrett J C, Anderson C A

Abstract excerpt

MOTIVATION: Existing microarray genotype-calling algorithms adopt either SNP-by-SNP (SNP-wise) or sample-by-sample (sample-wise) approaches to calling. We have developed a novel genotype-calling algorithm for the Illumina platform, optiCall, that uses both SNP-wise and sample-wise calling to more accurately ascertain genotypes at rare, low-frequency and common variants. RESULTS: Using data from 4537 individuals...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22500001
DOI: 10.1093/bioinformatics/bts180
PMCID: PMC3371828

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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