Article
Single nucleotide polymorphisms in the PRDX3 and RPS19 and risk of HPV persistence and cervical precancer/cancer.
PloS one - 1 Jan 2012
Safaeian Mahboobeh, Hildesheim Allan, Gonzalez Paula, Yu Kai, Porras Carolina, Li Qizhai, Rodriguez Ana Cecilia, Sherman Mark E, Schiffman Mark, Wacholder Sholom, Burk Robert, Herrero Rolando, Burdette Laurie, Chanock Stephen J, Wang Sophia S
Abstract excerpt
BACKGROUND: Host genetic factors might affect the risk of progression from infection with carcinogenic human papillomavirus (HPV), the etiologic agent for cervical cancer, to persistent HPV infection, and hence to cervical precancer and cancer. METHODOLOGY/PRINCIPAL FINDINGS: We assessed 18,310 tag single nucleotide polymorphisms (SNPs) from 1113 genes in 416 cervical intraepithelial neoplasia 3 (CIN3)/cancer...
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