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Article

Common variants in immune and DNA repair genes and risk for human papillomavirus persistence and progression to cervical cancer.

The Journal of infectious diseases - 1 Jan 2009

Wang Sophia S, Bratti M Concepcion, Rodríguez Ana Cecilia, Herrero Rolando, Burk Robert D, Porras Carolina, González Paula, Sherman Mark E, Wacholder Sholom, Lan Z Elizabeth, Schiffman Mark, Chanock Stephen J, Hildesheim Allan

Abstract excerpt

BACKGROUND: We examined host genetic factors to identify those more common in individuals whose human papillomavirus (HPV) infections were most likely to persist and progress to cervical intraepithelial neoplasia grade 3 (CIN3) and cancer. METHODS: We genotyped 92 single-nucleotide polymorphisms (SNPs) from 49 candidate immune response and DNA repair genes obtained from 469 women with CIN3 or cancer, 390 women...

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Identifiers

PMID: 19012493
DOI: 10.1086/595563
PMCID: PMC3690375

Genes

FANCA

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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