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Article

Improvement of defective cystic fibrosis airway epithelial wound repair after CFTR rescue.

The European respiratory journal - 1 Dec 2012

Trinh Nguyen Thu Ngan, Bardou Olivier, Privé Anik, Maillé Emilie, Adam Damien, Lingée Sarah, Ferraro Pasquale, Desrosiers Martin-Yvon, Coraux Christelle, Brochiero Emmanuelle

Abstract excerpt

Airway damage and remodelling are important components of lung pathology progression in cystic fibrosis (CF). Although repair mechanisms are engaged to restore the epithelial integrity, these processes are obviously insufficient to maintain lung function in CF airways. Our aims were therefore to study how the basic cystic fibrosis transmembrane conductance regulator (CFTR) defect could impact epithelial wound...

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Source

Identifiers

PMID: 22496330
DOI: 10.1183/09031936.00221711

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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