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Article

Downregulation of CFTR Is Involved in the Formation of Hypertrophic Scars.

BioMed research international - 1 Jan 2020

Zhou Yiwen, Zhao Yixuan, Du Hengyu, Suo Yinjun, Chen Hao, Li Haizhou, Liang Xiao, Li Qingfeng, Huang Xiaolu

Abstract excerpt

Hypertrophic Scars (HTSs) are a complex fibroproliferative disorder, and their exact mechanism is still not fully understood. In this study, we first found that cystic fibrosis transmembrane conductance regulator (CFTR) expression was downregulated in human hypertrophic scars at the RNA and protein levels by microarray data analysis, RT-PCR, and immunofluorescence (IF) staining. To validate that this...

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Identifiers

PMID: 31998800
DOI: 10.1155/2020/9526289
PMCID: PMC6970488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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