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Article

Insulin-like growth factor binding protein-3 suppresses vascular endothelial growth factor expression and tumor angiogenesis in head and neck squamous cell carcinoma.

Cancer science - 1 Jul 2012

Oh Seung-Hyun, Kim Woo-Young, Lee Ok-Hee, Kang Ju-Hee, Woo Jong-Kyu, Kim Jai-Hyun, Glisson Bonnie, Lee Ho-Young

Abstract excerpt

Angiogenesis, the process by which new blood vessels are recruited to existing ones, is essential for tumor development. Insulin-like growth factor (IGF) binding protein-3 (IGFBP-3), which modulates bioavailability of IGF, has been studied for its potential role in angiogenesis during tissue rege...

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Identifiers

PMID: 22494072
DOI: 10.1111/j.1349-7006.2012.02301.x
PMCID: PMC3465461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22494072-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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