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Article

IGF-binding proteins 3 and 4 are regulators of sprouting angiogenesis

4 Mar 2020

Abstract excerpt

Abstract Purpose We have previously identified insulin-like growth factor 2 (IGF2) and insulin-like growth factor 1 receptor (IGF1R) as essential proteins for tip cell maintenance and sprouting angiogenesis. In this study, we aim to identify other IGF family members involved in endothelial sprouting angiogenesis. Methods Effects on sprouting were analyzed in human umbilical vein endothelial cells (HUVECs) using...

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Share to 3D Printing in Biomedical Research
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PMID: 32133604
DOI: 10.1007/s11033-020-05339-0

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