Article
MicroRNA-193b Enhances Tumor Progression via Down Regulation of Neurofibromin 1
15 Jan 2013
Abstract excerpt
Despite improvements in therapeutic approaches for head and neck squamous cell carcinomas (HNSCC), clinical outcome has remained disappointing, with 5-year overall survival rates hovering around 40-50%, underscoring an urgent need to better understand the biological bases of this disease. We chose to address this challenge by studying the role of micro-RNAs (miRNAs) in HNSCC. MiR-193b was identified as an...
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